haku: @instructor Parkkonen, Lauri / yhteensä: 15
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Tekijä: | Ramkumar, Pavan |
Työn nimi: | Modeling the dynamics of human neuromagnetic brain rhythms |
Julkaisutyyppi: | Diplomityö |
Julkaisuvuosi: | 2008 |
Sivut: | 54 s. Kieli: eng |
Koulu/Laitos/Osasto: | Tietotekniikan laitos |
Oppiaine: | Informaatiotekniikka (T-61) |
Valvoja: | Kaski, Samuel |
Ohjaaja: | Hari, Riitta ; Parkkonen, Lauri |
OEVS: | Sähköinen arkistokappale on luettavissa Aalto Thesis Databasen kautta.
Ohje Digitaalisten opinnäytteiden lukeminen Aalto-yliopiston Harald Herlin -oppimiskeskuksen suljetussa verkossaOppimiskeskuksen suljetussa verkossa voi lukea sellaisia digitaalisia ja digitoituja opinnäytteitä, joille ei ole saatu julkaisulupaa avoimessa verkossa. Oppimiskeskuksen yhteystiedot ja aukioloajat: https://learningcentre.aalto.fi/fi/harald-herlin-oppimiskeskus/ Opinnäytteitä voi lukea Oppimiskeskuksen asiakaskoneilla, joita löytyy kaikista kerroksista.
Kirjautuminen asiakaskoneille
Opinnäytteen avaaminen
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Sijainti: | P1 Ark Aalto | Arkisto |
Avainsanat: | event-related dynamics generalized convolution magnetoencephalography mu rhythms oscillatory response predictive models Volterra kernels |
Tiivistelmä (eng): | As a precursor towards modelling event-related modulation of brain rhythms obtained by magneto encephalography (MEG), an oscillatory response function (ORF) is proposed. Analogous to the hemodynamic response function (HRF) in functional magnetic resonance imaging (fMRI), the ORF is a transformation applied to a boxcar function representing the stimulus time course, to predict the modulation of rhythmic brain activity. Both, linear and nonlinear parametric models for the ORF were derived in a generalized convolution framework. The corresponding convolution kernels were expanded as bilinear combinations of an orthonormal basis of discrete-time Laguerre functions. To estimate the model parameters, MEG data were acquired from 10 subjects during bilateral pneumotactile stimulation at two different stimulus rates in blocks of four different durations. The envelope of rhythmic activity in the 17-23 Hz frequency band was computed using the Hilbert transform, and subsequently averaged across blocks of each stimulus rate and duration. From a single representative channel over the rolandic region in each hemisphere, subject wise predictive models of envelope dynamics were derived. To study the generalizability of these models, MEG data were recorded from 5 different subjects with a different bilateral pneumotactile stimulation paradigm. A boxcar function was compared with the ORF-transformed boxcars as predictors of cortical minimum-norm current envelopes in a general linear model. The ORF-transformed boxcars localized rolandic activation in the 17-23 Hz band for tactile stimuli, to the primary motor cortex, better than the boxcar itself. As the models were able to predict well-known cortical generators of event-related mu rhythms, it is a worthwhile exercise to model the dynamics of rhythmic brain activity. |
ED: | 2009-01-21 |
INSSI tietueen numero: 36667
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