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| Author: | Litvinov, Ilia |
| Title: | Photophysical properties of chiral semiconductor nanocrystals in biological environments |
| Publication type: | Master's thesis |
| Publication year: | 2016 |
| Pages: | 70 Language: eng |
| Department/School: | Sähkötekniikan korkeakoulu |
| Main subject: | Micro- and Nanosciences (ELEC3037) |
| Supervisor: | Sun, Zhipei |
| Instructor: | |
| Electronic version URL: | http://urn.fi/URN:NBN:fi:aalto-201608263067 |
| Location: | P1 Ark Aalto 4449 | Archive |
| Keywords: | nanocrystals quantum dots dot-in-rods chirality cancer nanobiotechnology |
| Abstract (eng): | During the last decade much work has been focused on the use of nanostructures toward problems of biology and medicine. The issue of nanostructures application in cancer therapy depends on the effectiveness of the nanocrystals loading into cells. In this work chiral nanostructures based on CdSe/ZnS quantum dots (QD) and CdSe/CdS quantum dots in quantum rods (DiR) solubilized by L- and D-cysteine were formed using phase transfer method. We studied photophysical properties of chiral nanostructures in different biological media and analyzed spectral luminescent properties of complexes based on chiral nanostructures. Enantioselective cellular uptake of nanostructures was revealed, namely that L-cysteine capped nanocrystals uptake is higher than that of D-cysteine capped nanocrystals. Enantioselective interaction between chiral enantiomers of molecules and chiral nanostructures was detected. We believe this principle may lay the groundwork for novel approaches to studying biological objects and to application of nanostructures in medicine. |
| ED: | 2016-09-04 |
INSSI record number: 54279
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