search query: @supervisor Halme, Aarne / total: 354
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Author: | Nyqvist, Andreas |
Title: | Development of a process control system for a bioreactor with multiple vessels |
Utveckling av ett processtyrningssystem för en bioreaktor med flera kärl | |
Publication type: | Master's thesis |
Publication year: | 2007 |
Pages: | 62 Language: eng |
Department/School: | Automaatio- ja systeemitekniikan osasto |
Main subject: | Automaatiotekniikka (AS-84) |
Supervisor: | Halme, Aarne |
Instructor: | Pitkänen, Juha-Pekka |
OEVS: | Electronic archive copy is available via Aalto Thesis Database.
Instructions Reading digital theses in the closed network of the Aalto University Harald Herlin Learning CentreIn the closed network of Learning Centre you can read digital and digitized theses not available in the open network. The Learning Centre contact details and opening hours: https://learningcentre.aalto.fi/en/harald-herlin-learning-centre/ You can read theses on the Learning Centre customer computers, which are available on all floors.
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Location: | P1 Ark TKK 6619 | Archive |
Keywords: | bioprocess control bioprocess instrumentation Saccharomyces cerevisiae bioprocessreglering bioprocessinstrumentering Saccharomyces cerevisiae |
Abstract (eng): | Bioreactor control has become increasingly important in several industries. Bioreactors are used when developing and producing biotechnological products. For instance, these products include penicillin, vitamins, insulin, enzymes, beer, and wine. Due to the importance of these products, there are enormous economic incentives to optimize the bioprocesses needed to develop and produce the products. Proper process control contributes to the bioprocess optimization, for instance, by reducing the production costs, by increasing the yield, by providing better reproducibility, and by enabling better quality control. This thesis presents how a process control system was developed for a bioreactor with multiple vessels. The developed process control system enabled the operators to carry out cultivations in a temperature and pH controlled environment in each of the 15 bioreactor vessels. The control of the temperature and of the pH value is important since they affect essential process variables like the biomass growth and the product formation. Furthermore, the process control system enabled, to a limited extent, efficient cultivations of the yeast Saccharomyces cerevisiae due to the control of the ethanol concentration. Saccharomyces cerevisiae is a commonly used host organism for the production of various biotechnological products. Therefore, it is of great interest to be able to grow the organism efficiently. |
ED: | 2008-01-02 |
INSSI record number: 35038
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